- Author:
Kyung Ho KIM
1
;
Jae Kyoung SHIN
;
Sunwon KIM
;
Woo Hee CHO
;
Sung Soon KIM
Author Information
- Publication Type:Case Report
- Keywords: Takayasu arteritis; Tuberculosis; Prednisolone
- MeSH: Arteries; Granuloma; Humans; Hypertension*; Male; Methotrexate; Mycobacterium tuberculosis; Prednisolone; Renal Artery; Takayasu Arteritis*; Tuberculosis; Tuberculosis, Pulmonary*; Young Adult
- From:Korean Journal of Medicine 2017;92(1):66-69
- CountryRepublic of Korea
- Language:Korean
- Abstract: Takayasu's arteritis (TA) is an inflammatory disease involving large arteries and their branches. The etiology of TA is unknown, but infectious agents and genetic factors play a significant role in its pathogenesis. A relationship between TA and Mycobacterium tuberculosis infection has been suggested, since both diseases have similar chronic inflammatory lesions and the presence of occasional granulomas in arterial walls. Patients with TA have an increased immune response to Mycobacterium tuberculosis antigens, suggesting a role for this organism in the immunopathogenesis of the disease. Herein, we present a case of TA with active pulmonary tuberculosis in a Korean patient. A 21-year-old male presented with hypertension and active pulmonary tuberculosis. TA invading the renal artery was diagnosed while evaluating hypertension. The patient was treated with prednisolone, methotrexate, anti-hypertensive medications, and anti-tuberculosis medications.