Wells' Syndrome Associated with Churg-Strauss Syndrome.
- Author:
Soo Hyun LEE
1
;
Mi Ryung ROH
;
Hyunjoong JEE
;
Kee Yang CHUNG
;
Jin Young JUNG
Author Information
- Publication Type:Case Report
- Keywords: Churg-Strauss syndrome; Flame figures; Wells' syndrome
- MeSH: Biopsy; Blister; Cellulitis; Churg-Strauss Syndrome; Dermatitis; Dermis; Eosinophilia; Eosinophils; Humans; Purpura; Skin; Skin Diseases; Vasculitis
- From:Annals of Dermatology 2011;23(4):497-500
- CountryRepublic of Korea
- Language:English
- Abstract: Churg-Strauss syndrome (CSS) is a multisystem granulomatous vasculitis that is characterized by peripheral eosinophilia and the infiltration of eosinophils into systemic organs. The skin lesions of CSS consist mainly of palpable purpura and nodules. Wells' syndrome (WS) is a rare inflammatory dermatosis that is associated with recurrent granulomatous dermatitis and eosinophilia. Since these two diseases are rare, any overlap between them is very unusual. Herein, we report a patient with CSS, who initially presented a skin eruption of erythematous urticarial-plaques, vesicles, and blisters. Upon biopsy, the histology of these plaques indicated eosinophilic infiltration and "flame figures" within the dermis, which was consistent with a diagnosis of WS. Although the association between WS and CSS that was observed in our patient may be purely coincidental, it could also suggest a common pathogenetic background of these two distinct diseases, as both share several many common features.
