Multidrug-Resistant Tuberculosis Presenting as Miliary Tuberculosis without Immune Suppression: A Case Diagnosed Rapidly with the Genotypic Line Probe Assay Method.
10.4046/trd.2014.76.5.245
- Author:
Yousang KO
1
;
Ho Young LEE
;
Young Seok LEE
;
Junwhi SONG
;
Mi Yeong KIM
;
Hyun Kyung LEE
;
Jeong Hwan SHIN
;
Seok Jin CHOI
;
Young Min LEE
Author Information
1. Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Inje University Busan Paik Hospital, Inje University College of Medicine, Busan, Korea. ymleeim@paik.ac.kr
- Publication Type:Case Report
- Keywords:
Tuberculosis, Multidrug-Resistant;
Tuberculosis, Miliary;
Molecular Probe Techniques
- MeSH:
Adult;
Diagnosis;
Ethambutol;
Female;
Humans;
Isoniazid;
Korea;
Molecular Probe Techniques;
Rifampin;
Streptomycin;
Thorax;
Tuberculosis, Miliary*;
Tuberculosis, Multidrug-Resistant*
- From:Tuberculosis and Respiratory Diseases
2014;76(5):245-248
- CountryRepublic of Korea
- Language:English
-
Abstract:
Miliary tuberculosis (TB) is a rare extrapulmonary form of TB, and there have been only two reports of miliary TB associated with infection with multidrug-resistant (MDR)-TB pathogen in an immunocompetent host. A 32-year-old woman was referred to our hospital because of abnormal findings on chest X-ray. The patient was diagnosed with MDR-TB by a line probe assay and was administered proper antituberculous drugs. After eight weeks, a solid-media drug sensitivity test revealed that the pathogen was resistant to ethambutol and streptomycin in addition to isoniazid and rifampicin. The patient was then treated with effective antituberculous drugs without delay after diagnosis of MDR-TB. To the best of our knowledge, this is the first case of miliary TB caused by MDR-TB pathogen in Korea.
