Choriocarcinoma in Posterior Mediastinum: A case Report.
- Author:
Soo Sung KIM
1
;
Han Ik BAE
;
Jung Ran KIM
;
Young Hyun LEE
;
Jae Chul SHIM
;
Gyu Chun LEE
Author Information
1. Department of Thoracic and Cardiovascular Surgery, College of Medicine, Dongguk University, Korea.
- Publication Type:Case Report
- Keywords:
choriocarcinoma;
mediastinum
- MeSH:
Adult;
Brain;
Brain Neoplasms;
Cerebral Hemorrhage;
Chest Pain;
Choriocarcinoma*;
Cough;
Dyspnea;
Female;
Humans;
Male;
Mediastinum*;
Ovary;
Pregnancy;
Thorax;
Tomography, X-Ray Computed;
Uterus
- From:The Korean Journal of Thoracic and Cardiovascular Surgery
1997;30(4):462-466
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Primary mediastinal choriocarcinoma is characteristically seen in young males presenting with the symptomes of cough, chest pale, and gynccomastia. A 33-year-old woman was admitted to the hospital because of severe dyspnea and chest pain which was aggravated rapidly 2 or 3 days ago. Posterior mcdiastinal mass measuring about 1 cm in diameter was seen in Chest P-A, left lateral view of chest, and chest CT. Serum beta-HCG level was markedly elevated up to 200,000 mIxt. Whole body CT and other studies could not find any lesion on ovary and uterus. But, a single nodule nEeasuring about 1 cm in diameter was identified in the brain CT. The tumor cells (syncytiotrophoblastic cells) from resected mass revealed positivity on i histochemical staining for beta-HCG. She was treated with EMA-CO after resection of tumor, But, 7 months later, she was readmitted and showed cerebral hemorrhage due to metastatic choriocarcinoma. She was operated again for the brain tumor, and was doing well for further 7 months.