The Association between Obesity Indices in Adolescence and Carotid Intima-media Thickness in Young Adults: Kangwha Study.
10.3961/jpmph.2008.41.2.107
- Author:
Yoo Jung LEE
1
;
Chung Mo NAM
;
Hyeon Chang KIM
;
Nam Wook HUR
;
Il SUH
Author Information
1. Graduate School of Public Health, Yonsei University, Seoul, Korea.
- Publication Type:Original Article ; English Abstract
- Keywords:
Obesity;
Carotid artery thrombosis;
Adult;
Adolescence
- MeSH:
Adolescent;
Adult;
Blood Glucose/analysis;
Blood Pressure;
Carotid Arteries/*pathology;
Female;
Humans;
Korea/epidemiology;
Lipids/blood;
Male;
Obesity/*pathology/physiopathology;
Prospective Studies;
Sex Factors;
Tunica Intima/*pathology;
Waist-Hip Ratio
- From:Journal of Preventive Medicine and Public Health
2008;41(2):107-114
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVES: The aim of this study is to investigate the association between obesity indices (body mass index, weight, waist-hip ratio and waist circumference) in adolescents and the carotid intima-media thickness (C-IMT) in early adulthood. We also wanted to identify the best predictor for C-IMT among these obesity indices. METHODS: This study used community-based prospective cohort study, known as the Kangwha Study, and the data we used were from subjects who were 16-years old in 1996 (defined as "adolescencec") and 25 years-old in 2005 (defined as "early adulthoodc"). The 256 subjects (113 men and 143 women) who were used for analysis participated in both follow-ups, and they underwent B-mode ultrasonography of the carotid arteries at the early adulthood follow-up. Obesity indices were defined as the body mass index, weight, waist-hip ratio and waist circumference. The C-IMT was defined as the mean of the maximal IMT of each common carotid artery. The C-IMT and obesity indices associations were evaluated via multivariable regression, logistic regression and the receiver-operator characteristic curve analyses. RESULTS: In men, all the obesity indices in adolescence were showed to have statistically significant positive association with C-IMT in early adulthood. However, no such relationship was showed in women. On multiple regression and logistic regression analysis, the waist-hip ratio showed the biggest relationship with the C-IMT among the 4 obesity indices. However, there were no statistical significant differences and no best predictor was found. For the women, the obesity incidences and C-IMT showed no relationships. CONCLUSIONS: This study suggested that obesity in adolescence was related to an increase C-IMT in healthy young Korean men.
