Solitary Fibrous Tumor of the Kidney: A Report of Two Cases with Review of Literature.
- Author:
Sun A KIM
1
;
Jung Eun HWANG
;
Jae Y RO
;
Kyung Ja CHO
;
Cheryn SONG
;
Mi Jung KIM
Author Information
1. Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. mjkim1103@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Solitary fibrous tumor;
Kidney;
Immunohistochemistry
- MeSH:
Adult;
Blood Vessels;
Diagnosis, Differential;
Humans;
Immunohistochemistry;
Keratins;
Kidney;
Male;
Melanoma;
Nephrectomy;
Pleura;
Solitary Fibrous Tumors
- From:Korean Journal of Pathology
2010;44(4):420-425
- CountryRepublic of Korea
- Language:English
-
Abstract:
Solitary fibrous tumor (SFT) is a benign mesenchymal neoplasm usually occurring in the pleura. Kidney is one of the rarest sites for SFT. We report here on two cases of renal SFT found in 30-year-old and 33-year-old men with review of the literatures. Both cases manifested as well-enhanced solid masses in kidney and radical nephrectomies were done. The tumors consisted of bland-looking spindle cells arranged in short, ill-defined fascicles and storiform pattern with characteristic hemangiopericytoma-like blood vessels. The tumor cells were strongly positive for CD34 and CD99, focally positive for bcl-2, and negative for cytokeratin and human melanoma black-45 on immunohistochemical stainings. Possibility of SFT should be considered in the differential diagnosis of a renal mass which consists of benign-looking spindle cells and hemangiopericytomatous blood vessels. Immunohistochemical staining for CD34 is essential to confirm the renal solitary fibrous tumor.
