- Author:
Ji Young PARK
1
;
Ju Young CHOI
;
Jung Ji MIN
;
Yun Su SIM
;
Gun Woo PYUN
;
Youn Ju NA
;
Min Jung KANG
;
In Sook KANG
;
Si Nae LEE
;
Yookyung KIM
;
Jee Hyong JEONG
;
Jin Hwa LEE
;
Eun Mee CHEON
;
Jung Hyun CHANG
Author Information
- Publication Type:Case Report
- Keywords: Idiopathic hypereosinphilic syndrome
- MeSH: Angiography; Biopsy; Bone Marrow; Brain; Carotid Artery, Internal; Cerebral Infarction; Constriction, Pathologic; Eosinophilia; Eosinophils; Fibrosis; Humans; Hypereosinophilic Syndrome*; Liver; Lung Diseases, Interstitial; Lung*; Middle Aged
- From:Tuberculosis and Respiratory Diseases 2005;59(1):97-103
- CountryRepublic of Korea
- Language:Korean
- Abstract: Hypereosinophilic syndrome (HES) is characterized by a sustained eosinophilia of 1,500/mm3 or more in the absence of any known causes or the signs and symptoms of organ involvement. We report a 64-year-old man with HES initially presenting with involvement of the liver and bone marrow. Despite controlling the eosinophilia by corticosteroid, he developed a cerebral infarction and later progressive interstitial pneumonia. Brain angiography revealed a severe stenosis of the proximal right internal carotid artery (ICA) and a complete obstruction of the intracranial ICA. An open lung biopsy revealed fibrosis and lymphoplasma cell infiltration without eosinophils, which were consistent with nonspecific interstitial pneumonia.