Endobronchial Aspergilloma: Report of 10 Cases and Literature Review.
10.3349/ymj.2011.52.5.787
- Author:
Jeong Eun MA
1
;
Eun Young YUN
;
You Eun KIM
;
Gi Dong LEE
;
Yu Ji CHO
;
Yi Yeong JEONG
;
Kyoung Nyeo JEON
;
In Seok JANG
;
Ho Cheol KIM
;
Jong Deok LEE
;
Young Sil HWANG
Author Information
1. Department of Internal Medicine, College of Medicine, Gyeongsang National University, Jinju, Korea. hochkim@gnu.ac.kr
- Publication Type:Case Reports ; Review
- Keywords:
Endobronchial aspergilloma
- MeSH:
Adult;
Aged;
Bronchi/pathology;
Bronchography;
Bronchoscopy;
Female;
Humans;
Male;
Middle Aged;
Pulmonary Aspergillosis/*diagnosis/pathology/radiography;
Republic of Korea;
Retrospective Studies
- From:Yonsei Medical Journal
2011;52(5):787-792
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: A retrospective investigation of the clinical and radiologic features as well as the bronchoscopic appearance was carried out in patients with endobronchial aspergilloma. MATERIALS AND METHODS: Ten patients with endobronchial aspergilloma diagnosed by bronchoscopy and histological examination were identified at the Gyeongsang University Hospital of Korea, from May 2003 to May 2009. RESULTS: The patients included 9 men and 1 woman, and the age of the patients ranged from 36 to 76 (median, 58 years). The associated diseases or conditions were: previous pulmonary tuberculosis in 7 patients, lung cancer in 2 patients, pulmonary resection in 1 patient, and foreign body of the bronchus in 1 patient. The chest radiologic finding showed fibrotic changes as a consequence of previous tuberculosis infection in 6 patients and a mass-like lesion in 2 patients. Two patients had a co-existing fungus ball, and an endobronchial lesion was suspected in only 2 patients on the CT scan. The bronchoscopic appearance was a whitish to yellow necrotic mass causing bronchial obstruction in 7 patients, foreign body with adjacent granulation tissue and whitish necrotic tissue in 1 patient, whitish necrotic tissue at an anastomosis site in 1 patient, and a protruding mass with whitish necrotic tissue in 1 patient. CONCLUSION: An endobronchial aspergilloma is a rare presentation of pulmonary aspergilosis and is usually incidentally found in immunocompetent patients with underlying lung disease. It usually appears as a necrotic mass causing bronchial obstruction on bronchoscopy and can be confirmed by biopsy.
