Pyogenic Liver Abscess: Changes in Clinical Features over the Last 10 Years.
10.3904/kjm.2015.88.6.663
- Author:
Joo Ho PARK
1
;
Tae Hee LEE
;
Min Gyu KANG
;
Mi Young LEE
;
Myung Jun LEE
;
Jin Sil PYO
;
Jung Ho PARK
;
Hoon Sup KOO
;
Kyung Ho SONG
;
Yong Seok KIM
;
Sun Moon KIM
;
Kyu Chan HUH
;
Young Woo CHOI
;
Young Woo KANG
Author Information
1. Department of Internal Medicine, Konyang University Hospital, Konyang University College of Medicine, Daejeon, Korea. green740@naver.com
- Publication Type:Original Article
- Keywords:
Liver abscess;
Klebsiella pneumoniae;
Drainage
- MeSH:
Abscess;
Alcoholics;
Bacteria;
Bacterial Infections;
Chills;
Drainage;
Fever;
Humans;
Klebsiella pneumoniae;
Length of Stay;
Liver;
Liver Abscess;
Liver Abscess, Pyogenic*;
Male;
Medical Records;
Prevalence;
Sepsis
- From:Korean Journal of Medicine
2015;88(6):663-671
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND/AIMS: A pyogenic liver abscess is an acute bacterial infection that can potentially lead to life-threatening sepsis. This study examined the clinical features and changing trends of pyogenic liver abscess over the last 10 years. METHODS: We investigated patient characteristics, laboratory findings, blood and abscess culture results, location and characteristics of the abscess, and treatment modality in the medical records of 146 patients. We divided them into three groups by period: period 1, 23 patients in 2002-2003; period 2, 46 patients in 2007-2008; and period 3, 77 patients in 2012-2013. RESULTS: The mean patient age was 64.3 +/- 15.1 years and 87 of the 146 patients were male (59.6%). Period 2 had a higher prevalence of chronic alcoholics (30.4% vs. 10.4%) and lower prevalence of fever and chills (73.9% vs. 92.2%) compared with period 3. Klebsiella pneumoniae was the most commonly cultured bacteria and the microbiological findings did not differ among the three periods. Pyogenic liver abscesses were more common in the right liver. The lengths of hospital stay and treatment modalities were similar in all three periods. CONCLUSIONS: Although there were slight differences in symptoms among the periods, there were no changes in the liver abscess characteristics, i.e., location, size, and culture results. As there were no changes, the treatment strategy also did not change. We should continue to investigate the clinical features of liver abscess.
