A Case of Tubulointerstitial Nephritis and Uveitis with Fanconi Syndrome.
10.3904/kjm.2015.88.6.711
- Author:
Miyeon KIM
1
;
Hyun Woo KIM
;
Ji Young KIM
;
Jinho JEONG
;
Eun Jung PARK
;
Jinseok KIM
;
So Mi KIM
Author Information
1. Department of Internal Medicine, Jeju National University Hospital, Jeju National University School of Medicine, Jeju, Korea. zhidao79@naver.com
- Publication Type:Case Report
- Keywords:
Nephritis, Interstitial;
Uveitis;
Fanconi syndrome
- MeSH:
Acidosis, Renal Tubular;
Adolescent;
Adult;
Anorexia;
Arthralgia;
Child;
Fanconi Syndrome*;
Fatigue;
Female;
Fever;
Glycosuria, Renal;
Humans;
Hypokalemia;
Hypophosphatemia, Familial;
Middle Aged;
Nephritis, Interstitial*;
Rare Diseases;
Uveitis*;
Vomiting
- From:Korean Journal of Medicine
2015;88(6):711-714
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Tubulointerstitial nephritis and uveitis (TINU) syndrome is a rare disease that comprises 4.7% of acute interstitial nephritis. With reno-ocular manifestations, TINU syndrome is accompanied by symptoms such as fever, fatigue, malaise, anorexia, vomiting, and arthralgia. TINU syndrome is reported mainly in children or adolescent girls, and it is rare in adults. Although TINU syndrome can present with multiple renal tubular defects, Fanconi syndrome characterized by generalized impairment of proximal tubular function, leading to renal glucosuria, hyperuricosuria, hyperphosphaturia, proximal renal tubular acidosis, and kaliuresis leading to hypokalemia, has rarely been described. We report a case of TINU syndrome with Fanconi syndrome in a 46-year-old HLA B27-positive Korean woman.
