Meningovascular and Spinal form of Neurosyphilis Presenting as Multiple Cranial Nerve Palsy, Cerebral Infarction and Meningomyelitis in a Human Immunodeficiency Virus Negative-Patient: MR Imaging Features.
10.13104/jksmrm.2014.18.3.263
- Author:
Jin Ho HONG
1
;
Ha Young LEE
;
Myung Kwan LIM
;
Young Hye KANG
;
Kyung Hee LEE
;
Soon Gu CHO
Author Information
1. Department of Radiology, Inha University School of Medicine, Incheon, Korea. pengoon@gmail.com
- Publication Type:Case Report
- Keywords:
Neurosyphilis;
Meningovascular neurosyphilis;
Syphilitic myelitis;
Syphilitic meningomyelitis;
Meningitis;
Multiple cranial nerves
- MeSH:
Brain;
Cerebral Arteries;
Cerebral Infarction*;
Constriction, Pathologic;
Cranial Nerve Diseases*;
Cranial Nerves;
Diagnosis;
HIV*;
Humans;
Magnetic Resonance Imaging*;
Meninges;
Meningitis;
Middle Aged;
Neurosyphilis*;
Posterior Cerebral Artery;
Spinal Cord;
Spine;
Spirochaetales;
Syphilis;
Tabes Dorsalis;
Treponema pallidum;
Vestibulocochlear Nerve
- From:Journal of the Korean Society of Magnetic Resonance in Medicine
2014;18(3):263-268
- CountryRepublic of Korea
- Language:English
-
Abstract:
Neurosyphilis is a rare infection of the brain and spinal cord caused by a spirochete named Treponema pallidum. We describe the magnetic resonance imaging of a 53-year-old man with syphilis who manifested as both meningovascular, and spinal meningomyelitic types, which involved the optic, trigeminal, facial and vestibulocochlear nerves, both middle and left posterior cerebral arteries, thoracic spinal cord and meninges of the lumbar spine. This case report suggests that neurosyphilis should be considered as a possible diagnosis in patients showing complex brain and spinal imaging features. These features include enhancing meningeal lesions with multiple cranial nerve involvement, stenoses in large to medium size cerebral arteries, and intramedullary and meningeal lesions of spine.
