A Comparison of the Use of Contrast Media with Different Iodine Concentrations for Multidetector CT of the Kidney.
10.3348/kjr.2011.12.6.714
- Author:
Seung Chai JUNG
1
;
Seung Hyup KIM
;
Jeong Yeon CHO
Author Information
1. Department of Radiology, Seoul National University College of Medicine, Seoul, Korea, Institute of Radiation Medicine and Kidney Research Institute, Seoul National University Medical Research Center, Seoul 110-744, Korea. kimsh@radcom.snu.ac.kr
- Publication Type:Original Article ; Comparative Study
- Keywords:
Kidney;
CT;
Contrast media;
Iodine concentration
- MeSH:
Animals;
Aortography;
Artifacts;
Contrast Media/*chemistry;
Iodine/*analysis/*diagnostic use;
Iopamidol/chemistry/*diagnostic use;
Kidney/*radiography;
Kidney Cortex/radiography;
*Multidetector Computed Tomography;
Rabbits
- From:Korean Journal of Radiology
2011;12(6):714-721
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: To determine the optimal iodine concentration of contrast media for kidney multidetector computed tomography (MDCT) by comparing the degree of renal parenchymal enhancement and the severity of the renal streak artifact with contrast media of different iodine concentrations. MATERIALS AND METHODS: A 16-row MDCT was performed in 15 sedated rabbits by injection of 2 mL contrast media/kg body weight at a rate of 0.3 mL/sec. Monomeric nonionic contrast media of 250, 300, and 370 mg iodine/mL were injected at 1-week intervals. Mean attenuation values were measured in each renal structure with attenuation differences among the structures. The artifact was evaluated by CT window width/level and three grading methods. The values were compared with iodine concentrations. RESULTS: The 370 mg iodine/mL concentration showed significantly higher cortical enhancement than 250 mg iodine/mL in all phases (p < 0.05). There was however no significant difference in the degree of enhancement between the 300 mg iodine/mL and 370 mg iodine/mL concentrations in all phases. There is a significant difference in attenuation for the cortex-outer medulla between 250 mg iodine/mL and 300 mg iodine/mL (p < 0.05). The artifact was more severe with a medium of 370 mg iodine/mL than with 250 mg iodine/mL by all grading methods (p < 0.05). CONCLUSION: The 300 mg iodine/mL is considered to be the most appropriate iodine concentration in an aspect of the enhancement and artifact on a kidney MDCT scan.
