A Case of Bilateral Oncocytomatosis in Chronic Renal Failure.
- Author:
Kyung Il PARK
1
;
Hye Yeon PARK
;
Sang Youb HAN
;
Jung Wook SEO
;
Han Seong KIM
;
Jae Yoon RO
Author Information
1. Department of Internal Medicine, College of Medicine, Inje University, Korea. hansy@medimail.co.kr
- Publication Type:Case Report
- Keywords:
Oncocytoma;
Kidney;
Renal failure
- MeSH:
Adenoma, Oxyphilic;
Atrophy;
Carcinoma, Renal Cell;
Colloids;
Cytoplasm;
Eosinophils;
Female;
Humans;
Incidence;
Iron;
Kidney;
Kidney Failure, Chronic*;
Middle Aged;
Mitosis;
Nausea;
Renal Insufficiency;
Sclerosis;
Vimentin;
Vomiting
- From:Korean Journal of Nephrology
2004;23(4):644-648
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Renal oncocytoma is a uncommon benign tumor originating from the intercalated cells of the collecting duct, which occurs with an overall incidence of 3% to 7% among all renal tumors. Bilateral, multicentric renal oncocytoma is rare, especially in chronic renal failure. We report a case of 59-year-old woman with bilateral oncocytoma with renal failure. She presented nausea and vomiting for one month, and had no previous past medical history. Abdominal sonography and computed tomography revealed variable sized homogenous mass on both kidneys. Microscopic examination showed large polygonal cells with abundant eosinophilic and granular cytoplasm. Surrounding renal parenchyma revealed marked atrophy and sclerosis with a few intact glomeruli and tubules. We could exclude renal cell carcinoma because tumor cells were negative for CK7, CK20, vimentin, and Hale's colloidal iron staining, and did not show perinuclear halo and mitosis.
