Duodenal adenocarcinoma following a neuroendocrine tumor in the duodenum.
10.3904/kjim.2014.29.1.96
- Author:
Bun KIM
1
;
Ji Hye HUH
;
Youngsook KIM
;
Moon Jae CHUNG
;
Jeong Youp PARK
;
Si Young SONG
;
Seung Woo PARK
Author Information
1. Division of Gastroenterology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. swoopark@yuhs.ac
- Publication Type:Case Reports
- Keywords:
Neuroendocrine tumors;
Duodenal neoplasms;
Drug therapy
- MeSH:
Adenocarcinoma/*diagnosis/drug therapy;
Antineoplastic Agents/therapeutic use;
Duodenal Neoplasms/*diagnosis/drug therapy;
Humans;
Male;
Middle Aged;
Neoplasms, Second Primary/*diagnosis/drug therapy;
Neuroendocrine Tumors/*diagnosis/drug therapy
- From:The Korean Journal of Internal Medicine
2014;29(1):96-100
- CountryRepublic of Korea
- Language:English
-
Abstract:
Primary duodenal adenocarcinoma is a rare malignant neoplasm accounting for 0.3% of all gastrointestinal tract carcinomas. We herein present one case of duodenal adenocarcinoma after duodenal neuroendocrine carcinoma. Poorly differentiated duodenal neuroendocrine carcinoma with liver metastasis (TxNxM1) was confirmed, and eight cycles of palliative chemotherapy (5-fluorouracil/etoposide/cisplatin) were administered. The patient was then in a clinically complete response status. About 1 year later, newly developed adenocarcinoma was detected at the same site. It was completely surgically resected, and the patient was cured.