- Author:
Dong Jin PARK
1
;
Sung Ji LEE
;
Tae Jong KIM
;
Yong Wook PARK
;
Eunsin BAE
;
Eun Suk KANG
;
Shin Seok LEE
Author Information
- Publication Type:Case Report
- Keywords: Bruton-type agammaglobulinemia; Rheumatoid arthritis; Anti-rheumatic agents
- MeSH: Adult; Agammaglobulinemia; Antirheumatic Agents; Arthritis; Arthritis, Infectious; Arthritis, Rheumatoid; Bronchitis; Genetic Diseases, X-Linked; Humans; Male; Meningitis; Otitis Media; Pneumonia
- From:Journal of Rheumatic Diseases 2012;19(2):95-99
- CountryRepublic of Korea
- Language:Korean
- Abstract: Bruton-type agammaglobulinemia is primary hypogammaglobulinemia followed by severe recurrent infection, including bacterial otitis media, bronchitis, pneumonia, and meningitis. Septic arthritis is a main musculoskeletal disorder that can occur in association with Bruton-type agammaglobulinemia. But the development of rheumatoid arthritis (RA) is rarely reported in a patient with hypogammaglobulinemia. Here, we describe a case of 34-year-old male with Bruton-type agammaglobulinemia, who presented with multiple symmetric polyarthritis. He was diagnosed as having a RA according to ACR criteria. His symptoms of polyarthritis had been improved after the introduction of medications including DMARDs (disease modifying anti-rheumatic drugs). Our case suggests that RA can be developed in the setting of agammaglobulinemia, and even in this situation, anti-rheumatic agents were effective to control arthritis without complication such as severe infection.