Application of a New Spirometric Reference Equation and Its Impact on the Staging of Korean Chronic Obstructive Pulmonary Disease Patients.
10.3349/ymj.2012.53.2.363
- Author:
Yong Il HWANG
1
;
Eun Ji KIM
;
Chang Youl LEE
;
Sunghoon PARK
;
Jeong Hee CHOI
;
Yong Bum PARK
;
Seung Hun JANG
;
Cheol Hong KIM
;
Tae Rim SHIN
;
Sang Myeon PARK
;
Dong Gyu KIM
;
Myung Goo LEE
;
In Gyu HYUN
;
Ki Suck JUNG
Author Information
1. Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Hallym University Medical Center, Anyang, Korea. pulmoks@hallym.ac.kr
- Publication Type:Original Article
- Keywords:
Spirometry;
reference equation;
COPD;
diagnosis;
stage
- MeSH:
Adult;
Aged;
Aged, 80 and over;
Asian Continental Ancestry Group;
Female;
Humans;
Korea;
Male;
Middle Aged;
Pulmonary Disease, Chronic Obstructive/*diagnosis/pathology;
Retrospective Studies;
Spirometry/*methods
- From:Yonsei Medical Journal
2012;53(2):363-368
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: A new spirometric reference equation was recently developed from the first national chronic obstructive pulmonary disease (COPD) survey in Korea. However, Morris' equation has been preferred for evaluating spirometric values instead. The objective of this study was to evaluate changes in severity staging in Korean COPD patients by adopting the newly developed Korean equation. MATERIALS AND METHODS: We evaluated the spirometric data of 441 COPD patients. The presence of airflow limitation was defined as an observed post-bronchodilator forced expiratory volume in one second/forced vital capacity (FEV1/FVC) less than 0.7, and the severity of airflow limitation was assessed according to GOLD stages. Spirometric values were reassessed using the new Korean equation, Morris' equation and other reference equations. RESULTS: The severity of airflow limitation was differently graded in 143 (32.4%) patients after application of the new Korean equation when compared with Morris' equation. All 143 patients were reallocated into more severe stages (49 at mild stage, 65 at moderate stage, and 29 at severe stage were changed to moderate, severe and very severe stages, respectively). Stages according to other reference equations were changed in 18.6-49.4% of the patients. CONCLUSION: These results indicate that equations from different ethnic groups do not sufficiently reflect the airflow limitation of Korean COPD patients. The Korean reference equation should be used for Korean COPD patients in order to administer proper treatment.
