Effect of Low-dose Rocuronium on Tracheal Intubating Conditions during Induction of 8 vol% Sevoflurane with Remifentanil.
- Author:
Youn Suk SON
1
;
Kyu Don CHUNG
;
Hyun Sook CHO
;
Sang Mook LEE
;
Keon Hee RYU
;
Su Hwa KIM
Author Information
1. Department of Anesthesiology and Pain Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. nmoney@korea.com
- Publication Type:Original Article ; Randomized Controlled Trial
- Keywords:
intubation condition;
remifentanil;
rocuronium;
sevoflurane
- MeSH:
Anesthesia;
Hemodynamics;
Humans;
Incidence;
Intubation
- From:Anesthesia and Pain Medicine
2007;2(4):257-261
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: We evaluated the effect of low doses of rocuronium on tracheal intubating conditions and hemodynamic changes during induction of anesthesia with 8 vol% sevoflurane and remifentanil 1microg/kg. METHODS: Eighty four patients were randomized into one of three groups; Group I, II, III. Each group received normal saline, 0.3, 0.45 mg/kg of rocuronium respectively. Predetermined drugs for each group and remifentanil 1microg/kg were administered during induction of 8 vol% sevoflurane. After induction of 8 vol% sevoflurane, tracheal intubation was preformed. The tracheal intubation conditions and hemodynamic responses to tracheal intubation were assessed. RESULTS: Tracheal intubation was successful in all patients. The incidence of clinically acceptable intubating conditions was 79% in Group I, 100% in Group II, and 100% in Group III. There was no significant difference in intubating condition between Group II and Group III. The hemodynamic responses to tracheal intubation were blunted in all groups. CONCLUSIONS: After induction with 8 vol% sevoflurane and remifentanil 1microg/kg, low-dose rocuronium provides more satisfactory tracheal intubation conditions.