Two Separated Ileal Adenocarcinomas in Neurofibromatosis Type 1.
10.3349/ymj.2007.48.6.1039
- Author:
Seal HWANGBO
1
;
Jiyoun KIM
;
Hyun KIM
;
Jongok KIM
;
Changsuk KANG
;
Hyekyung LEE
Author Information
1. Department of Radiology, College of Medicine, Catholic University of Korea, Daejeon St. Mary's Hospital, Deajeon, Korea.
- Publication Type:Case Report
- Keywords:
Neurofibromatosis;
ileum;
adenocarcinoma
- MeSH:
Adenocarcinoma/complications/*pathology;
Adult;
Humans;
Ileal Neoplasms/complications/*pathology;
Ileum/pathology;
Intestinal Mucosa/pathology;
Male;
Neurofibromatosis 1/complications/*pathology
- From:Yonsei Medical Journal
2007;48(6):1039-1042
- CountryRepublic of Korea
- Language:English
-
Abstract:
Patients with neurofibromatosis-1 (NF-1) have increased susceptibility to a variety of malignancies. Here, we document a rare case of two separated ileal adenocarcinomas in NF-1. The adenocarcinomas were surrounded by a diffuse tubular adenomatous lesion of the mucosa, and ganglion cells were scattered in the NF background. We found this case meaningful for several reasons: two separated adenocarcinomas arising in an unusual ileal segment, the association with precancerous tubular adenoma, and the presence of ganglion cells, which suggests ganglioneuromatosis in NF-1.
