Comparative study of typical and atypical benign epilepsy with centrotemporal spikes (Rolandic epilepsy).
10.3345/kjp.2008.51.10.1085
- Author:
Junhyuk SONG
1
;
Kyuha LEE
;
Sajun CHUNG
Author Information
1. Department of Pediatrics, College of Medicine, Kyunghee University, Seoul, Korea. sajchung@khmc.or.kr
- Publication Type:Comparative Study ; Original Article
- Keywords:
Benign epilepsy with centrotemporal spikes (BECT);
Typical benign rolandic epilepsy;
Atypical benign rolandic epilepsy;
Worralls criteria
- MeSH:
Age of Onset;
Agenesis of Corpus Callosum;
Atrophy;
Dilatation;
Epilepsy, Rolandic;
Humans;
Neuroimaging;
Recurrence;
Retrospective Studies;
Seizures
- From:Korean Journal of Pediatrics
2008;51(10):1085-1089
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: This study aims to examine and compare the features of rolandic epilepsy. METHODS: Of 158 patients selected retrospectively, 116 had typical (group A) and 42 had atypical (group B) rolandic epilepsy, as defined by Worrall's criteria. RESULTS: The age at onset of the seizures in group Awas 8.6+/-2.0 y and 6.2+/-1.7 y in group B (P>0.05). Among the 40 patients who underwent neuroimaging studies (25 patients in group Aand 15 patients in group B), abnormal findings in group B included ventricular dilatation, mild cortical atrophy, and partial agenesis of corpus callosum. group A had no abnormal findings. The frequency of seizures was 2.0+/-1.0 and 2.3+/-1.2 per month in groups A and B respectively. Seizure control from the initial anticonvulsant treatment was achieved within 3 months in group A, and 3 to 12 months in group B. A 2-year remission rate was noted in 105 patients in group A and in 38 patients in group B. Of these, the recurrence rate after 2 y was 13 in group A and 12 in group B. CONCLUSION: Age of onset of seizures, gender, frequency of seizures before therapy, and 2-y remission rate were not significantly different in the 2 groups. However, neuroimaging abnormalities, the time to achieving seizure control from the initial anticonvulsant treatment, and the recurrence rate after being seizure-free for 2 y were significantly different in the 2 groups.
