An Experience of Finding Compatible Blood for Transfusion in Liver Transplant recipient with Unexpected Antibodies of anti-C, anti-Jka and anti-Dia.
- Author:
Dong Chan KIM
1
;
Mi Sook YOUN
;
Eun Young SONG
;
Jong Hoon KIM
;
Bum Ryoul CHOI
;
Deok Ja OH
;
Young Chul OH
;
Kyou Sup HAN
Author Information
1. Department of Laboratory Medicine, Seoul National University Hospital, Korea. kshanmd@snu.ac.kr
- Publication Type:Case Report
- Keywords:
Anti-C;
anti-Jka;
anti-Dia;
Unexpected antibody;
Antihumanglobuline phase;
Crossmatching
- MeSH:
Antibodies*;
Blood Group Incompatibility;
Humans;
Liver Transplantation;
Liver*;
Red Cross;
Transplantation*
- From:Korean Journal of Blood Transfusion
2002;13(2):181-186
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
It is very important to prevent hemolytic transfusion reaction. We experienced 1 case of transfusion in liver transplantation patient with multiple unexpected antibodies. On crossmatching for 20 pRBC (packed red blood cells), weak reactions were observed in room temperature, but strong reactions were observed in 37 , and AHG (antihuman globulin) phase. The patient had unexpected antibodies of anti-C, anti-Jka, anti-Dia. The probabilitis of compatible blood of anti-C, anti-Jka, anti-Dia in Koreans had been reported to be 14.2%, 32.8%, and 90%, respectively. We received 217 units of C antigen-negative pRBCs prepared by typing of 2679 type B pRBCs from Central, Eastern and Southern Blood Center of the Korean Red Cross. From the 217 units, 60 units of pRBCs compatible with patient's serum in AHG phase were prepared in our laboratory. The hemolytic tranfusion reaction can be successfully prevented by aid of Blood Center of Korean Red Cross and it should be emphasized that performing crossmatching including AHG phase is very important.
