The Optimal Concentration of Ropivacaine in Combination with Butorphanol 50micro gram/ml for Patient-Controlled Epidural Analgesia.
10.4097/kjae.2002.43.6.749
- Author:
Dong Hee KIM
1
Author Information
1. Department of Anesthesiology, College of Medicine, Dankook University, Cheonan, Korea. anesdhkim@hanmail.net
- Publication Type:Original Article
- Keywords:
Butorphanol;
cesarean section;
patient-controlled epidural analgesia (PCEA);
ropivacaine
- MeSH:
Analgesia;
Analgesia, Epidural*;
Analgesics, Opioid;
Anesthetics, Local;
Butorphanol*;
Cesarean Section;
Female;
Incidence;
Nausea;
Pregnancy;
Vomiting
- From:Korean Journal of Anesthesiology
2002;43(6):749-754
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Opioids may be used in a dose-sparing capacity with local anesthetics to reduce the dose needed. This study examined the efficacy of different concentrations of ropivacaine combined with butorphanol 50 micro gram/ml to provide postoperative analgesia. METHODS: Sixty parturients were received epidural infusion with 0.075% ropivacaine (Group 1: n = 20), 0.1% ropivacaine (Group 2: n = 20) and 0.15% ropivacaine (Group 3: n = 20) in combination with butorphanol 50 micro gram/ml using patient-controlled epidural analgesia (PCEA) after cesarean section. PCEA was started with basal infusion of 4 ml of PCEA solution and 4 ml of bolus infusion at 10 min of lockout interval. Using a visual analogue scale (VAS) assessed the degree of pain and incidences of side effects were checked. RESULTS: Total infusion doses of ropivacaine were significantly higher in group 3, and butorphanol consumption were significantly lower in group 3 (P<0.05). The incidences of nausea, vomiting and sedation were significantly higher in group 1 (P<0.05). There were no significantly differences in VAS pain score and other side effects among the groups. CONCLUSIONS: This study suggests that 0.1% or 0.15% ropivacaine with butorphanol 50micro gram//ml for PCEA can provide the most effective analgesia with less side effects after cesarean section.
