A Case Report of Syndrome of Inappropriate Antidiuretic Hormone Induced by Pregabalin.
- Author:
Youn Joo JUNG
1
;
Dong Young LEE
;
Hae Won KIM
;
Hyun Sun PARK
;
Beom KIM
Author Information
- Publication Type:Case Report
- Keywords: Drug associated syndrome of inappropriate antidiuretic hormone secretion; Hyponatremia; Pregabalin
- MeSH: Central Nervous System; Edema; Humans; Hyponatremia; Inappropriate ADH Syndrome; Neuralgia; Pregabalin*; Weight Gain
- From:Electrolytes & Blood Pressure 2016;14(2):31-34
- CountryRepublic of Korea
- Language:English
- Abstract: The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is the most common cause of euvolemic hyponatremia, and many medications have been associated with SIADH. Pregabalin is a drug used for the treatment of neuropathic pain, though common adverse effects include central nervous system disturbance, peripheral edema, and weight gain. However, hyponatremia caused by pregabalin has been rarely reported. Here we report a patient with pregabalin-induced hyponatremia who met the criteria for SIADH; after discontinuation of the drug, his condition rapidly improved. This case can help clinicians diagnose and treat new-onset hyponatremia in patients who recently initiated pregabalin therapy.
