A Case of Rh Negative Brother and Sister, Both of Whose Parents Were Rh Positive.
- Author:
Soon LEE
1
;
Soo Sung KIM
Author Information
1. Department of Clinical Pathology, Sunlin Hospital, Pohang, Korea.
- Publication Type:Case Report
- Keywords:
Rh negative brother and sister
- MeSH:
Child;
Fathers;
Genotype;
Haplotypes;
Humans;
Immune Sera;
Korea;
Mothers;
Parents*;
Phenotype;
Siblings*
- From:Korean Journal of Blood Transfusion
1998;9(1):111-116
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The authors have experienced a case of Rh negative brother and sister, both of whose parents were Rh positive. On the testing by five major Rh antisera (anti D, anti C, anti E, anti c, and anti e), the phenotypes of his father and mother were each DccEe and DCCee, those of the brother and sister were ddCcee. Considering the possible genotypes, their genotype was only one Cde/cde in twenty-four combinations. The possibility of that Rh negative (Cde/cde) child could successively born by those parents was 0.00017, with reference to Rh haplotype frequency in Korea. So, this case is rare and showed that Rh negative child could be born by Rh positive parents.