Juvenile Generalized Pustular Psorasis Treated with Etretinate and Methotrexate.
- Author:
Jong Hyun PAIK
;
Pill Sung PARK
;
Young Ja CHOI
;
Ho Suk SUNG
- Publication Type:Case Report
- Keywords:
Etretinate;
Methotrexate;
Pustular psoriasis
- MeSH:
Acitretin*;
Child;
Chills;
Erythema;
Etretinate*;
Female;
Fever;
Humans;
Lakes;
Methotrexate*;
Psoriasis;
Skin;
Suppuration
- From:Korean Journal of Dermatology
1989;27(1):64-68
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A case of generalized pustular psoriasis in a 12 year-old girl is described. She had generalized pustular eruptions on erythematous base, presenting lake of pus, yellowish brown crusts and denudation associated with high fever and chills. With the administration of oral etretinate at a dose of 0.8mg/kg/day for 1 week, rapid and dramatic remission was achieved. About 3 months after her discharge, there developed another wave of new pustules with fever. She was again placed on etretinate therapy. However, there was no expected response as before with developing new pustules continuously. At that time, we tried combination therapy with etretinate and methotrexate. the pustules and erythema began to remit, with eventual clearing of the skin in 6 weeks.
