The Reference Values and Influencing Factors of TCD Measurements in 200 Normal Korean Adults.
- Author:
Gyung Whan KIM
1
;
Young Ho SOHN
;
Joon Hong LEE
;
Doo Soo KIM
;
Jeong Yeon KIM
;
Jin Soo KIM
Author Information
1. Department of Neurology and Institute of Brain Research, Yonsei University, College of Medicine, Korea.
- Publication Type:Original Article
- Keywords:
Transcranial doppler ultrasonography;
Cerebral artery;
Cerebral blood flow;
Pulsatility Index;
Vasomotor reactivity
- MeSH:
Adult*;
Arteries;
Basilar Artery;
Breath Holding;
Cerebral Arteries;
Female;
Humans;
Male;
Middle Cerebral Artery;
Reference Values*;
Ultrasonography, Doppler, Transcranial
- From:Journal of the Korean Neurological Association
1995;13(4):815-824
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The clinical utility of transcranial doppler ultrasonography (TCD) in cerebrovascular disease has been extended recently. Although number of studies have been performed to define normal reference values of TCD measurements, they have some limitations to be used as reference values which include relatively small number of subjects, lack of data about some cerebral vessels and/or parameters. This study was aimed to obtain clinically useful reference values of TCD measurements with consideration of the influence of age and sex in Korean adults, particularly who are in stroke-prone age group. We measured flow velocities, pulsatility indecies, side-to-side differences and vasomotor reactivities of all intra-and extracranial cerebral arteries using TCD in 209 normal Korean adults (age, 23-78 years; 94 men and 115 women), and analyzed the influence of age and sex on those measurements. With advancing age, subjects showed significant reduction in velocity measurements and increase in pulsatility indecies of most examined arteries. Females showed hight velocities of middle cerebral, internal carotid, vertebral and basilar artery and lower pulsatility indecies of middle cerebral arteries compared with males. Asymmetry measurements including side-to-side differences and asymmetry index, and ,breath holding index testing vasomotor reactivity were also measured and the normal range of those parameters were calculated. Since present study included large number of subjects, and checked paramenters of TCD in both extra- as well as intracranial cerebral arteries, we are convinced that these results can be used as a reference data of TCD measurements in Korean adults.
