Sleep Related Periodic Leg Movements.
- Author:
Yong Duk KIM
1
;
Sang Bock LEE
;
Myung Sik LEE
Author Information
1. Department of Neurology, Yongdong Severance Hospital Yonsei University, College of Medicine, Korea.
- Publication Type:Original Article
- MeSH:
Dopaminergic Neurons;
Humans;
Leg*;
Levodopa;
Neurilemmoma;
Neurons;
Paraparesis;
Paresthesia;
Parkinson Disease;
Pyramidal Tracts;
Restless Legs Syndrome
- From:Journal of the Korean Neurological Association
1995;13(4):913-923
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We describe 7 patients with sleep related periodic leg movements(SRPLM) associated with variable neurological diseases, including focal thoracic cord lesions(4 cases), idiopathic Parkinson's diseased case), recurrent aseptic meningitis(1 case), and subacute sensory polyneuropathy(l case). Four patients with SRPLM associated with thoracic cord lesions also had paraparesis, suggesting involvement of pyramidal tract in the genesis of SRPLM. All the other three patients had dysesthesia, and at least two of them had restless legs syndrome. SRPLM of a patient with a thoracic schwannoma disappeared completely after surgical removal of tumor. One patient with intramedullary thoracic cord lesion and one asociated with Parkinson's disease showed marked improvement of SRPLM after levodopa treatment. Damage to the pyramidal tract or abnormal sensory inputs seem to activate lumbosacral generator selectively. Such neuronal systems are suspected to be modulated by. The dopaminergic neuronal system and the neuronal structures related to sleep.
