Clinical observation of acute glyphosate intoxication.
- Author:
Ju Young LEE
1
;
Kyu Yoon HWANG
;
Il song NAM
;
Hyun Jin YIM
;
Eun Na KIM
;
Jae Hwa JUNG
;
Sun Kyu KIM
;
Eun Young LEE
;
Sae Yong HONG
Author Information
1. Department of Internal Medicine, College of Medicine, Soonchunghang University, Chunan, Korea.
- Publication Type:Original Article
- Keywords:
Organophosphorus compounds;
Poisoning;
Herbicides
- MeSH:
Anemia;
Anoxia;
Chungcheongnam-do;
Cough;
Dyspnea;
Eating;
Herbicides;
Humans;
Internal Medicine;
Korea;
Male;
Nausea;
Organophosphorus Compounds;
Pharyngitis;
Pneumonia, Aspiration;
Poisoning;
Respiratory Insufficiency;
Retrospective Studies;
Sputum;
Suicide;
Vomiting
- From:Korean Journal of Medicine
2001;60(4):383-387
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Although glyphosate, organophosphorus herbicide, has been used extensively in agricultural area, no clinical data of acute poisoning have been reported in Korea. The current study evaluated clinical characteristics of acute intoxication by glyphosate. METHODS: We retrospectively collect and analysed the clinical data of 16 acute glyphosate poisoned patients admitted to the department of internal medicine, Soonchunhyang University Chunan hospital from January 1999 through June 2000. RESULTS: 1) Thirteen of sixteen poisoning were male and mean age was 44.2 year-old. 2) The main cause of glyphosate ingestion was suicide intent (12 cases, 75%), and clinical severity was divided into 3 categories : mild (14 cases), moderate (1 case) and severe (1 case). 3) Nausea and vomiting were the most frequent clinical features (each 6 cases) and dyspnea (4 cases), cough (3 cases), sputum (3 cases) and sore throat (3 cases) were followed. Leucocytosis, hepatotoxicity, anemia, hypoxia and renal toxicity were observed in 9,8,5,6 and 3 cases, respectively. 4) No fatal case and severe complication, except 1 aspiration pneumonia and 1 acute respiratory failure, were observed in acute glyphosate poisonings. CONCLUSION: Our data supported that acute glyphosate poisoning dose not result in fatal in humans even after intentional ingestion of glyphosate.
