Minimal Change Nephrotic Syndrome After Apitoxin Therapy: A Case Report.
- Author:
Jong O KIM
1
;
Byung Chul SHIN
;
Hyun Lee KIM
;
Jong Hoon CHUNG
Author Information
1. Department of Internal Medicine, Chosun University College of Medicine, Korea. jhchung@chosun.ac.kr
- Publication Type:Case Report
- Keywords:
Minimal change nephrotic syndrome;
Apitoxin;
Corticosteroids
- MeSH:
Adrenal Cortex Hormones;
Adult;
Bee Venoms*;
Bees;
Biopsy;
Bites and Stings;
Edema;
Female;
Follow-Up Studies;
Humans;
Injections, Intramuscular;
Nephrosis, Lipoid*;
Nephrotic Syndrome;
Physical Examination;
Recurrence
- From:Korean Journal of Nephrology
2007;26(6):736-739
- CountryRepublic of Korea
- Language:English
-
Abstract:
Bee stings have previously been implicated in the development of nephrotic syndrome, but the reported cases in the literature are rare. Furthermore, there has been no case of nephrotic syndrome after bee venom (apitoxin) therapy. We experienced a 28-year-old female who developed generalized edema 6 days after an intramuscular injection of apitoxin. The physical examination and laboratory findings were relevant with nephrotic syndrome and the renal biopsy revealed minimal change nephrotic syndrome. The corticosteroid treatment induced prompt remission with resolution of edema and normalization of the laboratory findings. There was no relapse of the disease during the 6-month follow-up. We report this case together with brief review of literatures.
