Changes in N-terminal pro-B-type natriuretic peptide in a neonate with symptomatic isolated left ventricular noncompaction.
10.3345/kjp.2009.52.1.129
- Author:
Ji Hyeun SONG
1
;
Yeo Hyang KIM
;
Chun Soo KIM
;
Sang Lak LEE
;
Tae Chan KWON
Author Information
1. Department of Pediatrics, Keimyung University School of Medicine, Daegu, Korea. kimyhped@hanmail.net
- Publication Type:Case Report
- Keywords:
Newborn;
Myocardium;
Natriuretic peptide;
Brain
- MeSH:
Brain;
Cardiopulmonary Resuscitation;
Cyanosis;
Death, Sudden, Cardiac;
Echocardiography;
Heart Arrest;
Heart Failure;
Humans;
Infant, Newborn;
Myocardium;
Tachypnea
- From:Korean Journal of Pediatrics
2009;52(1):129-132
- CountryRepublic of Korea
- Language:English
-
Abstract:
We describe here our experience with a neonate presenting with cyanosis, grunting, and cardiome galy, who was diagnosed with isolated left ventricular noncompaction (IVNC) by echocardiography. The patient had high levels of N-terminal pro-B-type natriuretic peptide (NT pro-BNP) and symptoms of heart failure including poor feeding and tachypnea. During the period in which NT pro-BNP levels steadily increased, the patient suffered sudden cardiac arrest despite heart failure management. Following cardiopulmonary resuscitation, cardiac arrest was resolved, NT pro-BNP levels decreased, and all symptoms showed improvement. We consider that assessment of NT pro-BNP with cardiac functional analysis using echocardiography could help in the prediction of disease progress in IVNC.
