Prostate Cancer: Added Value of Subtraction Dynamic Imaging in 3T Magnetic Resonance Imaging with a Phased-array Body Coil.
10.3349/ymj.2008.49.5.765
- Author:
Jeong Sik YU
1
;
Jae Joon CHUNG
;
Soon Won HONG
;
Byung Ha CHUNG
;
Joo Hee KIM
;
Ki Whang KIM
Author Information
1. Department of Radiology, Yonsei University College of Medicine, Yongdong Severance Hospital, Seoul, Korea. yjsrad97@yuhs.ac
- Publication Type:Original Article ; Evaluation Studies
- Keywords:
Prostate;
prostate cancer;
magnetic resonance imaging;
subtraction imaging;
dynamic imaging
- MeSH:
Aged;
Humans;
Magnetic Resonance Imaging/*methods;
Male;
Middle Aged;
Prostate/pathology;
Prostatic Neoplasms/*diagnosis/pathology;
Retrospective Studies;
Sensitivity and Specificity
- From:Yonsei Medical Journal
2008;49(5):765-774
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: To determine the added value of dynamic subtraction magnetic resonance (MR) imaging for the localization of prostate cancer. MATERIALS AND METHODS: We examined 21 consecutive patients who underwent MR imaging in 3T unit with a phased-array body coil and then had radical prostatectomy. After T2-weighted fast spin-echo imaging, we performed a contrast-enhanced dynamic 3D gradient-echo imaging consisting of pre-contrast, 2 successive early-phased (first imaging was started just after the appearance of contrast material in the aortic bifurcation followed by second imaging 35 seconds after the initiation of first imaging) and one 5-minute delayed post-contrast series. Subtraction of pre-contrast images from corresponding post-contrast images of each phase was performed on the console. RESULTS: On ROC analysis, the overall accuracy (Az value) of dynamic imaging combined with subtraction imaging was higher than T2-weighted imaging (p = 0.001) or conventional dynamic imaging alone (p = 0.074) for localization of cancer foci regardless of their zonal locations. Among pathologically verified 81 lesions, the mean volume of detected lesions with the subtraction images (n = 49, 0.69cm3) was smaller than with T2-weighted images (n = 14, 1.05cm3) or conventional dynamic images (n = 43, 0.71cm(3)). CONCLUSION: For localization of small prostate cancer, additional subtraction for the dynamic imaging could be superior to both T2-weighted imaging and un-subtracted dynamic imaging.
