Staging of Hepatic Fibrosis: Comparison of Magnetic Resonance Elastography and Shear Wave Elastography in the Same Individuals.
10.3348/kjr.2013.14.2.202
- Author:
Jeong Hee YOON
1
;
Jeong Min LEE
;
Hyun Sik WOO
;
Mi Hye YU
;
Ijin JOO
;
Eun Sun LEE
;
Ji Young SOHN
;
Kyung Boon LEE
;
Joon Koo HAN
;
Byung Ihn CHOI
Author Information
1. Department of Radiology, Seoul National University College of Medicine, Seoul 110-744, Korea. jmsh@snu.ac.kr
- Publication Type:Original Article ; Comparative Study ; Research Support, Non-U.S. Gov't
- Keywords:
Hepatic fibrosis;
Elastography;
Ultrasound-based elastography;
Shear wave elastography;
Magnetic resonance elastography;
Cross-validation
- MeSH:
Adolescent;
Adult;
Elasticity Imaging Techniques/*methods;
Female;
Humans;
Linear Models;
Liver Cirrhosis/*diagnosis/ultrasonography;
*Liver Transplantation;
*Living Donors;
*Magnetic Resonance Imaging;
Male;
Middle Aged;
ROC Curve;
Sensitivity and Specificity
- From:Korean Journal of Radiology
2013;14(2):202-212
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: To cross-validate liver stiffness (LS) measured on shear wave elastography (SWE) and on magnetic resonance elastography (MRE) in the same individuals. MATERIALS AND METHODS: We included 94 liver transplantation (LT) recipients and 114 liver donors who underwent either MRE or SWE before surgery or biopsy. We determined the technical success rates and the incidence of unreliable LS measurements (LSM) of SWE and MRE. Among the 69 patients who underwent both MRE and SWE, the median and coefficient of variation (CV) of the LSM from each examination were compared and correlated. Areas under the receiver operating characteristic curve in both examinations were calculated in order to exclude the presence of hepatic fibrosis (HF). RESULTS: The technical success rates of MRE and SWE were 96.4% and 92.2%, respectively (p = 0.17), and all of the technical failures occurred in LT recipients. SWE showed 13.1% unreliable LSM, whereas MRE showed no such case (p < 0.05). There was moderate correlation in the LSM in both examinations (r = 0.67). SWE showed a significantly larger median LSM and CV than MRE. Both examinations showed similar diagnostic performance for excluding HF (Az; 0.989, 1.000, respectively). CONCLUSION: MRE and SWE show moderate correlation in their LSMs, although SWE shows higher incidence of unreliable LSMs in cirrhotic liver.
