Cardiac Troponin T and Cardiac Troponin I Levels in End Stage Renal Disease Patients Undergoing Hemodialysis : as Markers of Myocardial Injury.
- Author:
Hyeok Jin YOON
1
;
Sang Bong LEE
;
Yang Wook KIM
;
Yeong Hoon KIM
;
Woo Yeong CHUNG
;
Myeong You KIM
;
Jeong Nyeo LEE
Author Information
1. Department of Internal Medicine, College of Medicine, Inje University, Busan, Korea. yhjsy@hanmail.net
- Publication Type:Original Article
- Keywords:
cTnT;
cTnI;
Myocardial injury;
Hemodialysis
- MeSH:
Cause of Death;
Cholesterol;
Dialysis;
Electrocardiography;
Humans;
Hyperparathyroidism, Secondary;
Hypertension;
Incidence;
Kidney Failure, Chronic*;
Male;
Myocardial Ischemia;
Myoglobin;
Renal Dialysis*;
Risk Factors;
Sensitivity and Specificity;
Smoke;
Smoking;
Troponin I*;
Troponin T*;
Troponin*
- From:Korean Journal of Nephrology
2002;21(4):652-658
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: The main cause of death in maintenance hemodialyzed patients is cardiovascular event. Serum cardiac troponin T(cTnT) and I(cTnI) are increased in the serum of patients with chronic renal failure. METHODS: We studied the incidence of increased serum cTnT and cTnI, the differences of their positivity, and the myocardial injury and cardiovascular risk factors in 56 maintenance hemodialyzed patients (30 males, 26 females). We investigated the patients about smoking, diabetes, hypertension and anginal pain. Blood was obtained from the patients immediately before hemodialysis. Samples were analyzed for myoglobin, CPK, LDH, total cholesterol, hemoglobin, PTH, cTnT and cTnI. Also, we evaluated the duration and adequacy(Kt/V(urea)) of dialysis and ECG. cTnT was measured by ECLIA(reference value
