A Case of Recurrent In-Stent Restenosis with Abundant Proteoglycan Component.
10.4070/kcj.2003.33.9.827
- Author:
Bora YANG
1
;
Myung Ho JEONG
;
Ok Young PARK
;
Jung Ha KIM
;
Woo Seok PARK
;
Weon KIM
;
Young Keun AHN
;
Jeong Gwan CHO
;
Jong Chun PARK
;
Jung Chaee KANG
Author Information
1. The Heart Center of Chonnam National University Hospital, Gwangju, Korea. myungho@chollian.net
- Publication Type:Case Report
- Keywords:
Stents;
Restenosis;
Cells
- MeSH:
Angina, Unstable;
Arteries;
Atherectomy, Coronary;
Cell Proliferation;
Coronary Artery Disease;
Extracellular Matrix;
Humans;
Middle Aged;
Myocytes, Smooth Muscle;
Percutaneous Coronary Intervention;
Proteoglycans*;
Stents
- From:Korean Circulation Journal
2003;33(9):827-831
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A percutaneous coronary intervention (PCI) is known to be one of effective methods in the treatment of coronary artery disease. However, restenosis remains a major limitation to a PCI. Although neointimal cell proliferation is suspected to be the major cause of coronary stent restenosis, few histological characterizations of recurrent instent restenosis exist. We report a case of a 61-year-old man suffering from unstable angina due to secondary coronary in-stent restenosis in the proximal left anterior descending artery (LAD). An atherectomized tissue, obtained by a directional coronary atherectomy, showed myxoid tissue, characterized by a few stellate smooth muscle cells in the abundant extracellular matrix, which was blue-colored proteoglycan on modified Movat staining.
