Health-related Quality of Life Measurement with St. George's Respiratory Questionnaire in Post-tuberculous Destroyed Lung.
10.4046/trd.2008.65.3.183
- Author:
Byoung Hoon LEE
1
;
Young Sam KIM
;
Ki Deok LEE
;
Jae Hyung LEE
;
Sang Hoon KIM
Author Information
1. Department of Internal Medicine, Eulji General Hospital, Eulji University School of Medicine, Seoul, Korea. ksh1134@eulji.ac.kr
- Publication Type:Original Article
- Keywords:
Tuberculosis;
Quality of life;
Pulmonary function test
- MeSH:
Community Medicine;
Exercise Test;
Exercise Tolerance;
Humans;
Lung;
Quality of Life;
Surveys and Questionnaires;
Reproducibility of Results;
Respiratory Function Tests;
Tuberculosis;
Tuberculosis, Pulmonary
- From:Tuberculosis and Respiratory Diseases
2008;65(3):183-190
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: The control of active pulmonary tuberculosis is still an issue in community medicine. But there are also considerable needs for supportive management of symptomatic patients with post-tuberculous destroyed lung. Few studies have evaluated clinical characteristics and health-related quality of life in patients with post-tuberculous destroyed lung. METHODS: We evaluated lung function, exercise tolerance, HRCT and health-related quality of life measurements using the Korean version of St. George's Respiratory Questionnaire (SGRQ) in 22 patients with parenchymal damage to more than a half of one lung due to pulmonary tuberculosis. RESULTS: In the pulmonary function test, mixed defects and obstructive defects were observed in 10 (45.0%) and 9 (40.9%) of patients, respectively. In the cardiopulmonary exercise test, the mean VO2max% predicted (39.0%+/-10.9%) and O2 pulse% predicted (61.3%+/-13.6%) were markedly decreased. In the SGRQ, the impact score (mean 27.8+/-18.5) was significantly lower than the symptom score (mean 53.9+/-20.9) or activity score (mean 50.8+/-27.3) (p<0.05, p<0.01). Cronbach's alpha coefficient value for reliability was more than 0.7 for each subscale and total score. The total score showed a significant negative correlation with FEV1% predicted (r=-0.46, p<0.05) and SaO2 (r=-0.60, p<0.05). On HRCT, a median of 9 (range 5~15) bronchopulmonary segments were destroyed by less than half, which significantly correlated with SGRQ total score (r=-0.52, p=0.02). CONCLUSION: The reliability and validity of the Korean version of the SGRQ was acceptable for the measurement of health-related quality of life in patients with post-tuberculous destroyed lung.
