Imported tertian malaria resistant to primaquine.
- Author:
Dong Jib NA
1
;
Jong Dae HAN
;
Dong Youb CHA
;
In Kwan SONG
;
Hwan Won CHOI
;
Eun A CHUNG
;
Chan Wook PARK
;
Jong Sung CHOI
Author Information
1. Department of Internal Medicine, Sun General Hospital, Dae Jeon, Korea.
- Publication Type:Case Report
- Keywords:
Plasmodium vivax, primaquine, resistant
- MeSH:
Animal;
Antimalarials/therapeutic use*;
Case Report;
Chloroquine/therapeutic use;
Drug Resistance;
Human;
Malaria, Vivax/parasitology;
Malaria, Vivax/drug therapy*;
Male;
Middle Age;
Plasmodium vivax/growth & development;
Plasmodium vivax/drug effects;
Primaquine/therapeutic use*;
Recurrence
- From:The Korean Journal of Internal Medicine
1999;14(2):86-89
- CountryRepublic of Korea
- Language:English
-
Abstract:
In Plasmodium vivax and Plasmodium ovale malaria, some of the liver stage parasites remain dormant. The activation of these dormant forms (called hypnozoite) can give rise to relapse weeks, months or years after the initial infection. To prevent relapses, a course of primaquine may be given as terminal prophylaxis to patients. Different strains of Plasmodium vivax vary in their sensitivity to primaquine and, recently, cases of relapse of Plasmodium vivax after this standard primaquine therapy were reported from various countries. We reported a case of primaquine resistant malaria which initially was thought to be relapsed caused by loss of terminal prophylaxis.
