A Case of Plasma Cell Granuloma of Skull in a Patient with Systemic Lupus Erythematosus.
- Author:
Ji Seon OH
1
;
Gui Young KWON
;
Min Wook SO
;
Seong Ho CHOI
;
Yong Gil KIM
;
Seong Su NAH
;
Chang Keun LEE
;
Hee Bom MOON
;
Bin YOO
Author Information
1. Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. byoo@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Plasma cell granuloma;
Skull;
Systemic lupus erythematosus
- MeSH:
Adult;
Biopsy;
Brain;
Cell Proliferation;
Female;
Follow-Up Studies;
Granuloma, Plasma Cell*;
Headache;
Humans;
Lupus Erythematosus, Systemic*;
Magnetic Resonance Imaging;
Parietal Bone;
Plasma Cells*;
Plasma*;
Positron-Emission Tomography;
Recurrence;
Scalp;
Skull*
- From:The Journal of the Korean Rheumatism Association
2006;13(4):311-315
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Plasma cell granuloma, a form of inflammatory pseudotumor, is a rare nonneoplastic lesion that is characterized by cellular proliferation composed predominantly of polyclonal plasma cells with other inflammatory cells in fibrovascular background. We have experienced an unusual case of plasma cell granuloma of skull that developed in a patient with systemic lupus erythematosus (SLE). A 42-year-old female diagnosed with SLE 13 years ago has complained of palpable scalp mass and headache beginning ten days previously. A brain magnetic resonance imaging showed intensely enhanced soft tissue mass with focal bone defect in right parietal bone and whole body positron emission tomography suggested high possibility of malignancy. Surgical tumor removal was performed. Biopsy specimen revealed inflammatory proliferation predominantly with mature plasma cells which were determined to be polyclonal in immunostaining. Currently, 4 months after surgery, the patient are on regular follow-up with oral medications (prednisolone, hydroxychloroquine) for SLE without evidence of recurrence.
