A Case of Polymyositis Associated with Primary Biliary Cirrhosis.
- Author:
Tae Jin PARK
1
;
Gil Soon CHOI
;
Han Jung PARK
;
Dai Yeol JOE
;
Jae Wook CHUNG
;
Hae Sim PARK
;
Jae Youn CHEONG
;
Young Bae KIM
;
Chull SHIM
;
Chang Hee SUH
Author Information
1. Department of Allergy & Rheumatology, Ajou University School of Medicine, Suwon, Korea. chsuh@ajou.ac.kr
- Publication Type:Case Report
- Keywords:
Polymyositis;
Primary biliary cirrhosis
- MeSH:
Alkaline Phosphatase;
Autoimmune Diseases;
Biopsy;
Diagnosis;
Electromyography;
Female;
Humans;
Immunoglobulin M;
Immunoglobulins;
Inflammation;
Korea;
Liver;
Liver Cirrhosis, Biliary*;
Middle Aged;
Muscle Weakness;
Polymyositis*
- From:The Journal of the Korean Rheumatism Association
2006;13(4):348-352
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The coexistence of polymyositis and primary biliary cirrhosis is rare. Both are characterized by chronic inflammation and immunological abnormalities. We report a case of 54-year-old female patient presenting with these two autoimmune diseases. She exhibited symmetrical proximal muscle weakness and elevated serum levels of muscle enzymes. Polymyositis was confirmed by electromyography and muscle biopsy. The diagnosis of primary biliary cirrhosis was based on increased serum levels of alkaline phosphatase, IgM immunoglobulin, presence of antimitochodrial antibody and characteristic liver biopy findings. This is the first case who manifest polymyositis and primary biliary cirrhosis simultaneously in Korea.
