Five Month-Persistent Extrapyramidal Symptoms following a Single Injection of Paliperidone Palmitate: A Case Report.
10.9758/cpn.2017.15.3.288
- Author:
Seoyoung JANG
1
;
Jungmin WOO
Author Information
1. Department of Psychiatry, Catholic University of Daegu School of Medicine, Daegu, Korea.
- Publication Type:Case Report
- Keywords:
Long-acting injectable antipsychotics;
Paliperidone palmitate;
Extrapyramidal symptoms;
Schizophrenia
- MeSH:
Antipsychotic Agents;
Hand;
Humans;
Paliperidone Palmitate*;
Plasma;
Schizophrenia
- From:Clinical Psychopharmacology and Neuroscience
2017;15(3):288-291
- CountryRepublic of Korea
- Language:English
-
Abstract:
Long-acting injectable (LAI) antipsychotics are useful in the treatments for schizophrenic patients with poor adherence due to their maintaining feature of therapeutic plasma level without daily administrations. However, their long-lasting property can cause complicated problems such as a long-lasting side effect. We report a patient who experienced LAI-induced extrapyramidal symptoms (EPSs) for 5 months after a single injection. During that period, every trial to ameliorate this condition turned out to be a failure. The 3-month formulation of paliperidone palmitate is now close at hand. We have to be aware of possible long-lasting adverse events and confirm the tolerability to LAI before use.