Clinicopathological observation of the patients with isoniazid responsive inflammatory nodules on the legs.
- Author:
Kwang Hyun CHO
;
So Su CHUN
;
Joo Heung REE
;
Seung Chul LEE
- Publication Type:Original Article
- Keywords:
Isoniazid;
Inflammatory nodule
- MeSH:
Erythema Nodosum;
Humans;
Isoniazid*;
Korea;
Leg*;
Tuberculin;
Tuberculosis, Pulmonary;
Vasculitis
- From:Korean Journal of Dermatology
1992;30(5):644-650
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We performed a clinicopathological study of nineteen patients with chronic inflammatory nodose lesions of the legs which responded to the treatment with isolniazid. The results were summarized as follows: 1. Seven patients had a personal or family history of tuberculcsis and all patients showed a high tuberculin sensitivity. But, no one showed the evidence of active pulmonary tuberculosis. 2. The inflammatory nodules and swelling of the legs were resolved within 12 months in all cases. Resolution of the nodules was more rapid than that of leg swelling. 3. The clinical characteristics of the patients with chronic inflanimatory nodules were the same as those of the cases with erythema nodosum or erytiema induratum reported previously in Korea. The basic histopathologic process of inflarr matory nodules seemed to be vasculitis.
