Two cases of Darier's disease treated with etretinate.
- Author:
Jin Soo KANG
;
Tae Heung KIM
;
Ki Beom PARK
- Publication Type:Case Report
- Keywords:
Dariers disease;
Etretinate
- MeSH:
Abdomen;
Acantholysis;
Acitretin*;
Adolescent;
Adult;
Edible Grain;
Darier Disease*;
Etretinate*;
Fathers;
Follow-Up Studies;
Humans;
Recurrence;
Skin
- From:Korean Journal of Dermatology
1992;30(5):705-709
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report two cases of Darier's disease improved with Etretmate in the 44-year-old father and his 18-year-old son. Clinically, multiple dirty brownish, verrucous, discrete or confluent papules and plaques were noted on their back, abdomen, and face. Histopathologically, both of them demonstrated hyperkeratosis, suprabasal acantholysis, acantholytic cells in the lacunae, corpsronds, grains, and dyskeratotic cells. Oral Etretinate 30mg daily was given in both cases with remakable improvement 3 weeks after treatment. Six months later, they showed almost total clearin, of their skin lesions. No specific adverse effect was noted. There has been no evidence of recurrence for 6 months follow up period.
