Efficacy of Intracameral Lidocaine During Phacoemulsification in Vitrectomized Eye.
- Author:
Jong Lyul PARK
1
;
Jun HER
Author Information
1. Department of Ophthalmology, Busan Paik Hospital, InJe University Medical college, Korea. hereye@ijnc.ijne.ac.kr
- Publication Type:Clinical Trial ; Randomized Controlled Trial ; Original Article
- Keywords:
Cataract;
Corneal endothelial cell;
Intracameral lidocaine;
Phacoemulsification
- MeSH:
Anesthesia;
Anterior Chamber;
Busan;
Cataract;
Endothelial Cells;
Endothelium;
Endothelium, Corneal;
Humans;
Lidocaine*;
Phacoemulsification*;
Prospective Studies;
Vitrectomy
- From:Journal of the Korean Ophthalmological Society
2002;43(11):2136-3143
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: This study was designed to evaluate the efficacy of intracameral lidocaine injection on patient' s pain relief during phacoemulsification in vitrectomized eyes and the influence on the corneal endothelial cells. METHODS: A prospective, double blind clinical trial was performed on 60 eyes of 60 patients who had undergone phacoemulsification from October 2000 to February 2001 at Busan PAIK Hospital. Thirty eyes had prior vitrectomy. Before surgery specular microscopic examination was performed. The patients were divided into vitrectomized and nonvitrectomized groups, and the lidocaine or placebo (BSS) was injected into the anterior chamber of 15 eyes each in two subgroups within each group. Pain was assessed using a visual analogue scale before, during and after operation. Endothelial cells were examinined at one week, one month, and three months after operation with a specular microscope. RESULTS: In vitrectomized patients, intracameral lidocaine injection resulted in significantly lower intraoperative pain score. There were no significant differences in morphological changes of endothelium between lidocaine and placebo groups. CONCLUSIONS: Intracameral lidocaine injection with topical anesthesia had significant effect in intraoperative pain relief during phacoemulsification in vitrectomized eyes. There was no significant effects on corneal endothelium. We conclude that intracameral anesthesia is safe and reduces intraoperative pain in vitrectomized eyes.
