Chronic Inflammatory Demyelinating Polyneuropathy Developed during Interferon-beta Therapy in a Patient with Multiple Sclerosis.
- Author:
Chan Nyoung LEE
1
;
Byung Jo KIM
;
Kun Woo PARK
;
Seong Boem KOH
;
Ho Jung KIM
;
Dae Hie LEE
Author Information
1. Department of Neurology, Korea University College of Medicine, Seoul, Korea. nukbj@korea.ac.kr
- Publication Type:Case Report
- Keywords:
Multiple sclerosis;
Chronic inflammatory demyelinating polyneuropathy;
IFN beta
- MeSH:
Female;
Humans;
Interferon-beta*;
Interferons;
Multiple Sclerosis*;
Polyneuropathies*;
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating;
Steroids
- From:Journal of the Korean Neurological Association
2006;24(5):486-490
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Preliminary studies have evaluated the effects of interferon beta formulations in the treatment of chronic inflammatory demyelinating polyneuropathy (CIDP) because of pathogenic similarities between CIDP and multiple sclerosis (MS). However, the efficacy of Interferon, which has been widely used for relapsing-remitting MS, is controversial in CIDP. We report here a 31year old woman with relapsing-remitting type MS treated with IFN beta-1b over 2 years who developed overt CIDP. She responded favorably to steroids. This case suggests that IFN beta-1b treatment may not prevent development of CIDP.
