Magnetic Resonance Imaging Factors Predicting Re-excision in Breast Cancer Patients Having Undergone Conserving Therapy.
10.13104/jksmrm.2014.18.2.133
- Author:
Mijung JANG
1
;
Sun Mi KIM
;
Bo La YUN
;
Sung Won KIM
;
Eun Young KANG
;
So Yeon PARK
;
Jee Hyun KIM
;
Yeongmi KIM
;
Hye Shin AHN
Author Information
1. Department of Radiology, Seoul National University Bundang Hospital, Gyeonggi-do, Korea. kimsmlms@daum.net
- Publication Type:Original Article
- Keywords:
Breast;
Breast neoplasm;
Conservation therapy;
Diagnosis, Magnetic resonance imaging (MRI)
- MeSH:
Breast;
Breast Neoplasms*;
Humans;
Logistic Models;
Magnetic Resonance Imaging*
- From:Journal of the Korean Society of Magnetic Resonance in Medicine
2014;18(2):133-143
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: The aim of this study was to determine the magnetic resonance imaging (MRI) features associated with re-excision due to the presence of a positive margin after breast conserving therapy (BCT) in breast cancer patients. MATERIALS AND METHODS: We reviewed the records of 286 consecutive breast cancer patients who received BCT between January 2006 and December 2007. Among 246 patients who had undergone BCT, 38 (15.4%) underwent immediate further surgery due to positive margin status. We analyzed the MRI findings using chi2 test, Fisher's exact test and t tests. Multivariate logistic regression was conducted for prediction of re-excision. RESULTS: Tumor size (p < 0.001), lesion multiplicity (p = 0.003), and non-mass-like enhancement (NMLE) type on MRI (p < 0.001) were associated with margin involvement in BCT. On preoperative MRI, larger size (> or = 5 cm) (odds ratio = 2.96), NMLE (odds ratio = 3.81), and multifocal lesions (odds ratio = 2.54) were positively associated with re-excision. In cases involving NMLE, segmental distribution was associated with a greater likelihood of immediate re-excision. CONCLUSION: Larger size, multiplicity, and NMLE on MRI are significantly associated with re-excision after BCT in breast cancer patients. For NMLE lesions, the segmental distribution pattern was predictive of re-excision.
