A Successful Transplant of HLA-3 Loci Mismatched Umbilical Cord Blood into a Patient with Acute Myeloid Leukemia from an Unrelated Donor.
- Author:
Byoung Chul KWON
1
;
Kyung Mi SHIN
;
Sung Chul WON
;
Chuhl Joo LYU
;
Chang Hyun YANG
;
Hyun Ok KIM
Author Information
1. Department of Pediatrics, College of Medicine, Yonsei University, Seoul, Korea. cj@yumc.yonsei.ac.kr
- Publication Type:Case Report
- Keywords:
Cord blood transplantation;
HLA-3 loci mismatching;
Unrelated donor
- MeSH:
Blood Platelets;
Bone Marrow;
Fetal Blood*;
Granulocytes;
Hematopoietic Stem Cells;
Humans;
Leukemia, Myeloid, Acute*;
Male;
Stem Cells;
Umbilical Cord*;
Unrelated Donors*
- From:Journal of the Korean Pediatric Society
2002;45(7):912-916
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cord blood is a useful source of allogeneic hematopoietic stem cells for bone marrow reconstitution. The number of umbilical cord blood transplants is increasing worldwide. In this a case 15- month-old boy with acute myeloid leukemia was treated with umbilical cord blood transplant from an HLA-3 loci mismatched unrelated donor. Granulocyte recovery greater than 500/mm3 occurred at day 49, and the platelet recovered greater than 20,000/mm3 independent of transfusion at day 81 after stem cell infusion.
