The crisis of antimicrobial resistance: current status and future strategies.
10.5124/jkma.2010.53.11.999
- Author:
Jae Hoon SONG
1
;
Eun Jeong JOO
Author Information
1. Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. songjh@skku.edu
- Publication Type:Original Article
- Keywords:
Antimicrobial resistance;
Drug resistance, multiple;
Future strategies
- MeSH:
Acinetobacter baumannii;
Clinical Medicine;
Cooperative Behavior;
Cross Infection;
Delivery of Health Care;
Drug Resistance, Multiple;
Enterobacteriaceae;
Escherichia coli;
Gram-Negative Bacteria;
Hospitalization;
Humans;
Infection Control;
Klebsiella pneumoniae;
Korea;
Methicillin-Resistant Staphylococcus aureus;
Prevalence;
Pseudomonas aeruginosa;
Social Control, Formal;
Streptococcus pneumoniae;
Vaccination
- From:Journal of the Korean Medical Association
2010;53(11):999-1005
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The continuous emergence of new antimicrobial resistance in major human pathogens is a serious threat to clinical medicine, that increases mortality, morbidity, length of hospitalization, and the cost of healthcare. This review article focuses on the current status of antimicrobial resistance and future strategies to overcome antimicrobial resistance. In the community, multidrugresistant Streptococcus pneumoniae, community-associated methicillin-resistant Staphylococcus aureus (MRSA), and extended-spectrum beta-lactamaseproducing Enterobacteriaceae are major issues. In the hospital, an increasing prevalence of multidrug-resistant or pan-drug resistant gram-negative bacteria such as Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii are emerging problems, while MRSA still remains the major cause of nosocomial infections. Strategies to control antimicrobial resistance include effective antimicrobial treatment, vaccination, infection control and appropriate policies and regulations. Continuous surveillance activities both in Korea and in an international setting are essential. Control of antimicrobial resistance should be a national priority based on a multisectoral approach, and international collaboration.
