A Case of Renal Angiomyolipoma with Lymph Node-Associated Elevation of Tumor Markers.
- Author:
Yu Ah HONG
1
;
Hyung Wook KIM
;
Der Sheng SUN
;
Hae Mi LEE
;
Jin Young YOO
;
Hoon Kyo KIM
;
Byoung Yong SHIM
Author Information
1. Department of Internal Medicine, The Catholic University of Korea School of Medicine, Seoul, Korea. shimby@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Tumor markers, biological;
Angiomyolipoma;
Lymph nodes;
Tuberous sclerosis
- MeSH:
Adipose Tissue;
Angiomyolipoma;
Blood Vessels;
Kidney;
Lymph Nodes;
Myocytes, Smooth Muscle;
Tuberous Sclerosis;
Biomarkers, Tumor
- From:Korean Journal of Medicine
2011;80(Suppl 2):S287-S294
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Angiomyolipoma is a rare, benign, mesenchymal hamartomatous neoplasm consisting of a mixture of adipose tissue, smooth muscle cells, and anomalous blood vessels. The kidney is a common origin site, but extrarenal angiomyolipoma has been reported. Simultaneous involvement of the kidney and regional lymph nodes is uncommon, and may be confused with a metastatic malignant lymph node. Lymph node involvement in angiomyolipoma represents a multifocal invasion of the tumor, rather than metastatic disease. Tumor markers usually associate with malignancy but they have sometimes been detected in benign conditions. We report a case of bilateral renal angiomyolipoma with tuberous sclerosis simultaneously involving regional lymph nodes confused with metastatic malignant lymph node enlargement due to associated elevation of serum tumor markers.