A study of trabecular bone strength and morphometric analysis of bone microstructure from digital radiographic image.
- Author:
Seung Yun HAN
1
;
Sun Bok LEE
;
Sung Ook OH
;
Min Suk HEO
;
Sam Sun LEE
;
Soon Chul CHOI
;
Tae Won PARK
;
Jong Dae KIM
Author Information
1. Department of Oral and Maxillofacial Radiology and Dental Research Institute, College of Dentistry, Seoul National University, Korea. raychoi@snu.ac.kr
- Publication Type:Original Article
- Keywords:
bone;
radiography;
dental;
digital;
signal processing;
computer-assisted
- MeSH:
Elastic Modulus;
Fractals;
Mandible;
Radiography;
Skeleton;
Swine
- From:Korean Journal of Oral and Maxillofacial Radiology
2003;33(2):113-119
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To evaluate the relationship between morphometric analysis of bone microstructure from digital radiographic image and trabecular bone strength. MATERIALS AND METHODS: One hundred eleven bone specimens with 5 mm thickness were obtained from the mandibles of 5 pigs. Digital images of specimens were taken using a direct digital intraoral radiographic system. After selection of ROI (100x100 pixel) within the trabecular bone, mean gray level and standard deviation were obtained. Fractal dimension and the variants of morphometric analysis (trabecular area, periphery, length of skeletonized trabeculae, number of terminal point, number of branch point) were obtained from ROI. Punch sheer strength analysis was performed using Instron (model 4465, Instron Corp., USA). The loading force (loading speed 1 mm/min) was applied to ROI of bone specimen by a 2 mm diameter punch. Stress-deformation curve was obtained from the punch sheer strength analysis and maximum stress, yield stress, Young's modulus were measured. RESULTS: Maximum stress had a negative linear correlation with mean gray level and fractal dimension significantly (p< 0.05). Yield stress had a negative linear correlation with mean gray level, periphery, fractal dimension and the length of skeletonized trabeculae significantly (p< 0.05). Young's modulus had a negative linear correlation with mean gray level and fractal dimension significantly (p< 0.05). CONCLUSIONS: The strength of cancellous bone exhibited a significantly linear relationship between mean gray level, fractal dimension and morphometric analysis. The methods described above can be easily used to evaluate bone quality clinically.
