The Effect of Preoperative Dexamethasone on Profopol Injection Pain, Postoperative Nausea and Vomiting Undergoing Otolaryngology-Head and Neck Surgery.
10.4097/kjae.2006.50.5.490
- Author:
Cheol LEE
1
;
Tai Yo KIM
;
Yoon Kang SONG
;
Yong SON
;
Yong Kwan CHEONG
;
Min Soo KIM
Author Information
1. Department of Anesthesiology and Pain Medicine, School of Medicine, Wonkwang University, Iksan, Korea. ironyii@wonkwang.ac.kr
- Publication Type:Original Article
- Keywords:
dexamethasone;
injection pain;
nausea;
vomiting
- MeSH:
Administration, Intravenous;
Adult;
Dexamethasone*;
Hand;
Hospitalization;
Humans;
Incidence;
Nausea*;
Neck*;
Pain, Postoperative*;
Postoperative Nausea and Vomiting;
Propofol;
Recovery Room;
Tonsillectomy;
Veins;
Vomiting*
- From:Korean Journal of Anesthesiology
2006;50(5):490-494
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Induction with propofol has a high incidence of pain, as well as postoperative nausea and vomiting (PONV). The aim of this study was to assess the effect of a course of dexamethasone on the pain, postoperative nausea and vomiting associated with a Propofol injection, in patients undergoing otolaryngology-head and neck surgery. METHODS: One hundred twenty adults, 20-60 years of age, ASA physical status I or II, were allocated to one of two groups. Either dexamethasone 5 ml (8 mg) or saline 5 ml was administered intravenously to each group. After 60 seconds, propofol was injected into the patients' hand veins over a 30 second period and the patient was asked questions regarding the injection pain after 10 seconds. Postoperative nausea, vomiting and post-tonsilectomy pain were recorded in the recovery room (1 h after surgery) and in the hospitalization area (6 h after surgery). RESULTS: The severity and incidence of pain at the time of the propofol injection, PONV, and the level of post-tonsillectomy pain were significantly lower in the dexamethasone group than in the control group. CONCLUSIONS: The prophylactic intravenous administration of 8 mg dexamethasone is effective in reducing the severity of pain after a propofol injection and after the tonsillectomy, and decreased the incidence of PONV.
