A Case of Central Diabetes Insipidus in Patient with Non-small Cell Lung Cancer.
10.4046/trd.2004.57.3.284
- Author:
Eun Mi HWANG
1
;
You Kyoung OH
;
Ki Jo KIM
;
Yong Hyun KIM
;
Hyoung Kyu YOON
;
Jeong Sup SONG
Author Information
1. Division of Pulmonology, Department of Internal Medicine, The Catholic University of Korea, College of Medicine, Seoul, Korea. jssong@catholic.ac.kr
- Publication Type:Original Article
- Keywords:
Non-small cell lung cancer;
Central diabetes insipidus
- MeSH:
Carcinoma, Non-Small-Cell Lung*;
Deamino Arginine Vasopressin;
Diabetes Insipidus, Neurogenic*;
Diagnosis;
Humans;
Lung Neoplasms;
Neoplasm Metastasis;
Osmolar Concentration;
Paraneoplastic Syndromes;
Radiotherapy;
Water Deprivation
- From:Tuberculosis and Respiratory Diseases
2004;57(3):284-288
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Central diabetes insipidus (DI) is a disease caused by insufficient release of antidiuretic hormone. Central DI with lung cancer is very rare. Most of them are caused by the pituitary metastasis, and rarely, by the paraneoplastic syndromes. Central DI is diagnosed by the water deprivation test. The treatment consists of surgical resection, radiotherapy and administration of desmopressin. We report an unusual case of central DI with non-small cell lung cancer. The diagnosis was confirmed by water deprivation test. After the administration of desmopressin, the urine osmolarity was increased. The patient's symptoms and urine osmolarity were improved by intranasal desmopressin.