Multiple Gastrointestinal Tract MALT Lymphomas with Bone Marrow Involvement: A Case Report and Literature Review.
- Author:
Hyung Jun KIM
1
;
Jongha PARK
;
Young Don JOO
;
Soon Il LEE
;
Eun Ji LEE
;
Hyun Tae KIM
;
Ji Yeon KIM
Author Information
1. Department of Internal Medicine, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea. neakker@gmail.com
- Publication Type:Case Report
- Keywords:
Marginal zone B cell lymphoma;
Bone marrow;
Stomach and duodenum
- MeSH:
Bone Marrow Examination;
Bone Marrow*;
Colonoscopy;
Drug Therapy;
Duodenum;
Endoscopy, Gastrointestinal;
Gastrointestinal Tract*;
Humans;
Lymphoid Tissue;
Lymphoma;
Lymphoma, B-Cell, Marginal Zone*;
Male;
Middle Aged;
Pathology;
Spleen;
Stomach;
Thorax
- From:Korean Journal of Medicine
2014;86(5):593-597
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The stomach is the most common site of gastrointestinal tract lymphoma, while synchronous mucosa-associated lymphoid tissue (MALT) lymphomas of the stomach and duodenum are very rare. A literature review found no reported case of synchronous gastroduodenal MALT lymphomas with involvement of the bone marrow and spleen. Here, we describe the case of a 62-year-old male who was diagnosed with synchronous MALT lymphomas of the stomach and duodenum based on upper gastrointestinal endoscopy and pathology. Other staging evaluations, including colonoscopy, abdominopelvic and chest computed tomography (CT), 18F fludeoxyglucose-positron emission tomography (FDG-PET), and a bone marrow examination, showed involvement of the bone marrow and spleen. We diagnosed stage EIV MALT lymphoma and began systemic chemotherapy. We report the first case of MALT lymphomas arising synchronously in both the stomach and duodenum with bone marrow involvement and review the literature.